All the Good Bits
Net weight = 2 kg
Mycosorb A+ by Alltech is a toxin binder based on a specific strain of yeast, Saccharomyces cerevisiae, rich in glucans that have been shown to bind a broad range of mycotoxins including aflatoxins. It reduces the risk of mycotoxins by the process of adsorption. Adsorption is the process by which carbohydrate components of yeast and algae cell walls bind to mycotoxins, removing them from the digestive tract. This mechanism has been demonstrated through various peer-reviewed papers showing the involvement of Van der Waal’s and hydrogen bonds between mycotoxins and beta-1,3 and beta-1,6 glucans. These beta-glucans are the active components of Mycosorb.
My Horse Supplies chose this toxin binder product due to the significant research behind it. In animals, aflatoxins are known to affect liver function while ochratoxins are a group of potent nephrotoxins, contributing to kidney damage. Fumonisins are known to affect the liver as well as immune system.
If you are concerned about your hay being mouldy or are experiencing a fungus outbreak in your pasture, for example, Paspalum ergot fungus or certain strains of endophyte perennial Rye grass, consider a toxin binder. These plants and others are renowned for causing photosynthesisation, signs are sunburn and blistering on pink skin on faces and pasterns (generic term, greasy heel or mud fever). When an animal consumes a plant or chemical containing these pigments (e.g., polyphenolic), the pigments circulate to the skin where they are exposed to UV light, fluoresce and cause oxidative injury to the cells of the skin. Liver damage in a horse might not be noticed until the animal develops photosensitisation.
Mycosorb has other advantages, including:
- A low effective inclusion rate
- Broad spectrum reach and component broad spectrum reach
- High efficacy
- Binds mycotoxins without binding nutrients
- Excretion of toxins via the faeces
- Supports recovery of the immune system
Mycosorb has been verified by world renowned research institutes. Worldwide, Mycosorb is a highly successful technology with proven efficacy.
Feeding rate (per day) according to manufacturer:
Mix with feed. Ideally divide amount between meals if feeding more than once per day.
High rate for 500kg horse – 20 g per day (4 g per 100kg)
Standard for 500kg horse – 10 g per day (2 g per 100kg)
Saccharomyces cerevisiae is grown under specific conditions to allow for the formation of specific carbohydrates on its cell wall. Factors such as the sugar type used during the production of the yeast affect the types of specific carbohydrates that the Saccharomyces cerevisiae will produce. The correct sugar types are vital to produce the complex and mycotoxin-specific carbohydrate network found in Mycosorb A+ and so, are monitored closely by Alltech. Adsorption takes place in the digestive tract of animals between the binding sites of the specific carbohydrates and mycotoxins. The correct geometry of the binding sites is critical to ensure they interact correctly with mycotoxins. When a mycotoxin enters a binding site, van der waals forces and electrostatic forces form between the site and the mycotoxin, therefore removing the mycotoxin from the digestive tract. By understanding gene expression, Alltech is able to optimise the complex network of carbohydrates on the yeast cell wall, ensuring specificity with a range of different mycotoxins. As well as containing yeast, Mycosorb A+ also contains algae. The algae are heterotrophic and are also grown under specific conditions to produce specific carbohydrates for the adsorption of mycotoxins. Alone, algae has adsorption properties, however it is capable of targeting different mycotoxins to the yeast. Therefore, by combining the two, an even larger range of mycotoxins are able to be adsorbed. The unique technology behind Mycosorb A+ makes it the most advanced mycotoxin binder on the market. Feeding rate (per day) according to manufacturer: Research With over fifty-five peer-reviewed in vivo trials, Mycosorb’s mode of action is supported by 16 PhD and 19 Master projects, and has been awarded eight patents that protect its novel composition and proprietary production. Mycosorb Bibliography 2017 For an explanation of the process: Interesting article: Study: Mycotoxin Causes Bone Marrow Suppression, Hair LossClick For More Information
Mix with feed. Ideally divide amount between meals if feeding more than once per day.
High rate for 500kg horse – 20 g per day (4 g per 100kg)
Standard for 500kg horse – 10 g per day (2 g per 100kg)
https://balancedequine.com.au/images/PDFs/Mycosorb-Research.pdf
Quinn et al (2014) Secondary Plant Products Causing Photosensitization in Grazing Herbivores: Their Structure, Activity and Regulation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907879/
http://www.thehorse.com/articles/36278/study-mycotoxin-causes-bone-marrow-suppression-hair-loss?utm_source=Newsletter&utm_medium=health-news&utm_campaign=08-18-2015
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